alphagenome.models.variant_scorers.CenterMaskScorer

class alphagenome.models.variant_scorers.CenterMaskScorer(requested_output, width, aggregation_type)

Variant scorer for center mask scorers.

Variant scorer that aggregates ALT and REF values using a spatial mask centered around the variant before computing the difference. This scorer aggregates over the spatial axis and returns one score per output track.

requested_output

The requested output type (e.g., ATAC, DNASE, etc.)

width

The width of the mask around the variant.

aggregation_type

The aggregation type.

base_variant_scorer

The base variant scorer.

name

The name of the scorer (a composite of the above attributes that uniquely identifies a scorer combination).

is_signed

Whether this variant scorer is directional (such that scores may be negative or positive) or non-directional (scores are always positive).

to_proto()

Converts the scorer to its corresponding proto message.

Raises:

ValueError – If the requested output, width, or aggregation type is not supported.

Attributes

Table

base_variant_scorer
is_signed
name
requested_output
width
aggregation_type

CenterMaskScorer.base_variant_scorer

CenterMaskScorer.is_signed

CenterMaskScorer.name

CenterMaskScorer.requested_output: OutputType

CenterMaskScorer.width: int

CenterMaskScorer.aggregation_type: AggregationType

Methods

Table

to_proto()

CenterMaskScorer.to_proto()

Return type:

VariantScorer