alphagenome.data.gene_annotation.filter_to_mane_select_transcript

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alphagenome.data.gene_annotation.filter_to_mane_select_transcript#

alphagenome.data.gene_annotation.filter_to_mane_select_transcript(gtf)[source]#

Filter GTF entries to only the MANE select transcript.

Note that the MANE_Select tag only exists for the human GTF file.

Parameters:: gtf (DataFrame) – pd.DataFrame of GENCODE GTF entries. Must contain columns ‘tag’.
Return type:: DataFrame
Returns:: pd.DataFrame of GENCODE GTF entries subset to rows representing MANE select transcripts, which are transcripts that are well-supported, conserved, and expressed.