predict_variants

predict_variants#

DnaClient.predict_variants(intervals, variants, *, organism=Organism.HOMO_SAPIENS, requested_outputs, ontology_terms, progress_bar=True, max_workers=5)[source]#

Generate predictions for a sequence of DNA variants.

Parameters:

  • intervals (Interval | Sequence[Interval]) – DNA interval(s) to make predictions for.

  • variants (Sequence[Variant]) – DNA variants to make prediction for.

  • organism (Organism (default: <Organism.HOMO_SAPIENS: 9606>)) – Organism to use for the prediction.

  • requested_outputs (Iterable[OutputType]) – Iterable of OutputTypes indicating which subsets of predictions to return.

  • ontology_terms (Iterable[OntologyTerm | str] | None) – Iterable of ontology terms or curies to generate predictions for. If None returns all ontologies.

  • progress_bar (bool (default: True)) – If True, show a progress bar.

  • max_workers (int (default: 5)) – Number of parallel workers to use.

Return type:

list[VariantOutput]

Returns:

Variant outputs for each DNA interval and variant pair.