ContactMapScorer

class alphagenome.models.v2.variant_scorers.ContactMapScorer

Variant scorer for contact map scorers.

Variant scorer that quantifies local contact disruption between ALT and REF alleles. Uses a 1 Mb window centered around the variant to calculate the mean absolute difference of contact frequencies, for all interactions involving the variant-containing bin.

requested_output

The requested output type (e.g., CONTACT_MAPS).

base_variant_scorer

The base variant scorer.

name

The name of the scorer (a composite of the above attributes that uniquely identifies a scorer combination).

is_signed

Whether this variant scorer is directional (such that scores may be negative or positive) or non-directional (scores are always non-negative).

to_proto()

Converts the scorer to its corresponding proto message.