score_intervals

score_intervals#

DnaClient.score_intervals(intervals, conditions=None, interval_scorers=(), *, organism=Organism.HOMO_SAPIENS, cell_conditionings=None, cell_condition_names=None, progress_bar=True, max_workers=5)[source]#

Generate interval scores for a sequence of intervals.

Parameters:

  • intervals (Sequence[Interval]) – Sequence of DNA intervals to make prediction for.

  • conditions (Sequence[ModelCondition | str] | None (default: None)) – Optional sequence of conditions or composite curies to generate the prediction for.

  • interval_scorers (Sequence[GeneMaskScorer] (default: ())) – Sequence of interval scorers to use for scoring. If no interval scorers are provided, the recommended interval scorers for the organism will be used.

  • organism (Organism (default: <Organism.HOMO_SAPIENS: 9606>)) – Organism to use for the prediction.

  • cell_conditionings (Sequence[AnnData] | None (default: None)) – Optional sequence of expression conditioning inputs (AnnData).

  • cell_condition_names (Sequence[str] | None (default: None)) – Optional sequence of labels for expression conditioning. Must be provided when cell_conditionings is used.

  • progress_bar (bool (default: True)) – If True, show a progress bar.

  • max_workers (int (default: 5)) – Number of parallel workers to use.

Return type:

list[list[AnnData]]

Returns:

List of AnnData lists corresponding to score_interval outputs for each interval.